October 10 - 23, 2027
October 8 - 21, 2028
14 DAYS / 13 NIGHTS from $3,975
Our staff at 1-800-246-7238 is ready to help
Trip Highlights
Perhaps no other trek gets so close to many of the world's tallest mountains in such a short amount of time
Fully supported trek so you can pack a light daypack each day and fully enjoy the experience
An incredible cultural experience: our path to the "big mountains" winds through charming villages
Stay in comfortable traditional lodges called "Tea-houses" each evening on the trek
Hike through the spectacular Modi Khola Gorge - arguably the deepest in the world!
Tour Kathmandu and multiple UNESCO World Heritage sites. Learn about Buddhist and Hindu traditions
The Annapurna Sanctuary Trek—also known as the Annapurna Base Camp Trek—is truly spectacular.
One of Nepal’s shortest major treks, it delivers an extraordinary blend of rich cultural immersion and some of the most dramatic mountain scenery on Earth. This is a rare journey into the heart of the Himalaya—an experience few will ever have the opportunity to enjoy.
Our adventure begins in Kathmandu, a vibrant, bustling city where ancient traditions and diverse cultures intertwine. From there, a short flight takes us to the lakeside city of Pokhara, the gateway to the world’s tallest mountain range.
The trail winds through one of the deepest gorges on the planet, eventually leading to Annapurna Base Camp, a natural amphitheater encircled by towering Himalayan peaks. Along the way, we pass through bamboo forests and terraced fields, and connect with the warm, resilient mountain communities who call this region home.
Each evening, we relax in comfortable lodges, gathering for pre-dinner CME lectures—combining meaningful learning with an unforgettable high-altitude adventure.
Itinerary Snapshot
Annapurna Sanctuary Trek
Wilderness & Expedition Medicine CME
DAY 1 - Arrival in Kathmandu Arrive in Nepal’s vibrant capital and settle in at the historic Hotel Yak & Yeti, your home base for the journey ahead.
DAY 2 - Kathmandu Exploration & Course Kickoff Enjoy a guided tour of Kathmandu’s cultural and historic highlights, followed by time to relax. We’ll gather for CME sessions, participant introductions, and a full trip briefing at the Yak & Yeti.
DAY 3 - Fly to Pokhara & Begin the Journey Take a breathtaking flight to the lakeside city of Pokhara, then transfer to the trailhead as our trek into the Himalaya officially begins.
DAY 4 to DAY 11 - The Annapurna Sanctuary Trek Immerse yourself in one of the world’s great trekking experiences. Highlights include a sunrise over the Himalaya from Poon Hill, traversing deep gorges and alpine forests, and reaching the awe-inspiring amphitheater of Annapurna Base Camp (13,550 ft)—surrounded by some of the tallest peaks on Earth. We return to Pokhara at the end of the trek with time to unwind and explore the town.
DAY 12 - Pokhara at Leisure A full day to relax by the lake or choose from a variety of optional adventures and excursions.
DAY 13 - Return to Kathmandu & Farewell Celebration Fly back to Kathmandu and return to the Yak & Yeti. Spend the afternoon exploring on your own before gathering for a group farewell dinner to celebrate an unforgettable journey.
DAY 14 - Departure Day We’ll arrange airport transfers for your flight home from Kathmandu.
About Our Exceptional Professional Guides
This expedition is led by an elite team of Nepalese mountain professionals with decades of experience guiding in the Himalaya, including on Everest and throughout the Annapurna region. Their deep local knowledge, technical expertise, and commitment to safety create an environment where participants can fully focus on the experience.
Legendary Everest climber Pete Athans, who has summited Everest an extraordinary seven times, offers this endorsement:
“I can wholeheartedly recommend my friend Jiban Ghimire to organize your Khumbu experience. I’ve worked closely with this team for nearly 20 years and have complete confidence in their ability to deliver an outstanding expedition.”
From logistics and route selection to daily care on the trail, our guides are known for professionalism, warmth, and an exceptional ability to deliver world-class Himalayan journeys.
Dates & Pricing
Our trips typically sell out, so we recommend booking early to secure your spot. Prices are based on double occupancy.
Qualifications: The trek to Annapurna Base Camp is physically demanding and participants should be in good overall condition. No prior trekking or mountaineering experience is required. A spirit of adventure, flexibility, and a willingness to embrace long days on the trail and the inherent challenges of mountain travel are essential.
Trip includes: This trip includes three hotel nights in Kathmandu and two hotel nights in Pokhara, along with selected guided sightseeing in Kathmandu. Round-trip airfare between Kathmandu and Pokhara is included, as well as a professionally guided trek to Annapurna Base Camp. Porters and yaks will carry group gear during the trek, and all meals are provided while on the trail, with select meals included in Kathmandu.
Trip does not include: Medical evacuation insurance and helicopter transport—whether required for medical reasons or due to unforeseen weather delays—are not included.
October 10 - 23, 2027
$4,075 per person
$789 Optional CME Cost
(16 AMA PRA Category 1 Credits™)
$150 Nepal Government tax
Available - Filling Quickly
October 8 - 21, 2028
$4,300 per person
$789 Optional CME Cost
(16 AMA PRA Category 1 Credits™)
$150 Nepal Government tax
Available - Filling quickly
Questions? Ready to reserve your spot?
Speak to an expert at Bio Bio Expeditions - the award winning outfitter of this trip
1-800-246-7238
A few of the publications Bio Bio Expeditions has been featured in:
Testimonials From Your Colleagues
There is no better Wilderness Medicine course. Guide staff and logistics were great. Chemistry of the group was great.
Another fantastic CME! I cannot recommend this company and these wilderness CME courses enough! They are well thought out, well executed and very thoughtful.
Excellent education supplied on the CME trips partnered with Bio Bio Expeditions. I've been on 6 trips and the speakers have always been excellent and engaging. A really fun way to get CME with a couple relevant lectures a day.
Thanks again for hosting a great trip! It was like the summer camp that I wish I had gone on as a kid. What a great escape to not worry about anything and let you plan our activities and food. It was a little hard to return to my office and the real world afterwards.
Our group included both medical and non-medical hikers and all had an amazing experience. The guides were very informative and went out of their way to make sure all skill levels were able to complete the trek. The lecture format was flexible and adjusted to our hiking days. This was our second trip with Bio Bio and we will certainly be back.
Faculty was exceptional, inspirational and funny. The faculty has amazing experience that they communicate magnificently! Course content was balanced and interesting. Guide staff was skilled and wonderful. Perfect trip itinerary. Excellent meals.
This was such a great opportunity to experience hands on learning with wilderness experts. Era and Brian were great educators and awesome travel companions!
The Annapurna Sanctuary trek was my sixth Bio Bio/WME trek and as usual it was well planned with great guiding and accommodations. I'm already planning my next trek.
Amazing group of people to travel with!
Amazing trip, made possible by the confidence and competence of some great guides and porters. Santiago Ibanez of Bio Bio, in cooperation with the guides and porters of Shangri La Nepal Trek, worked together to make this trip very well put together. Several members of our group experienced unexpected medical emergencies and I always felt that things were very much under control and dealt with professionally. The depth of knowledge and understanding of the culture and geography by the people leading us was second to none.
My daughter Taylor had an incredible time. After this experience, she is determined to reach for the stars and become a doctor. The CMEs and getting to know doctors who inspired her along the way really have a profound effect on her
A truly magical experience. Our trip was nothing short of fantastic — truly a once-in-a-lifetime experience we hope to repeat. We took the trip as a combination honeymoon and family vacation. Our group of seven ranged in age from mid-20s to late 60s and everyone had a wonderful experience. We felt welcomed the entire time.
COURSE CONTENT INCLUDES
- Altitude Illness
- Hypothermia
- Frostbite and Other Cold Injuries
- Environmental Heat Illness
- Traveler's Diarrhea, Giardia & Other Waterborne Wilderness Infections
- Surviving the Unexpected Night Out
- Lightning Injuries
- Improvised Medical and Trauma Care
- Management of Fractures and Dislocations
- Preparing for Foreign Travel
- Backcountry Medical Kits
- Wilderness Wound Management
- Patient Assessment in Wilderness Settings
- Wilderness Dermatology
- Marine Hazards & Envenomations
- Snake Envenomation
CME ACCREDITATION INFORMATION
"This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint providership of the Center for Emergency Medical Education and Wilderness and Travel Medicine. The Center for Emergency Medical Education is accredited by the ACCME to provide continuing medical education for physicians."
The Center for Emergency Medical Education designates this live activity for a maximum of
16 AMA PRA Category 1 CreditsTM.
Physicians should claim only the credit commensurate with the extent of their participation in the activity.
This trip is planned, outfitted and conducted by Bio Bio Expeditions, or subcontractors arranged by Bio Bio Expeditions. Please note that Wilderness and Travel Medicine, LLC is responsible for the CME Educational content only. Wilderness and Travel Medicine reserves the right to change or substitute the faculty for any CME course without advance or prior notice to participants.
For more information or to register for this trip please call
Bio Bio Expeditions at 1-800-246-7238
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Skills Course Rafting & Mt. Shasta
June 11 - 16, 2028
Deluxe African Safari: Zimbabwe
July 26 - Aug 3, 2028
Aug 27 - Sept 6, 2028
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Sept 1-6, 2028
Sept 14 - 22, 2028
Sept 28 - Oct 8, 2028
Oct 1 - 15, 2028
Oct 8 - 21, 2028
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Oct 15 - 20, 2028
UPCOMING CME DESTINATIONS BY DATE
Jan 16 - 23, 2027
Japan Ski & Snowboard Adventure
Jan 25 - Feb 1, 2027
National Conference on Wilderness Medicine: Big Sky Ski Resort, MT
Feb 20 - 24, 2027
Japan Ski & Snowboard Adventure
Feb 4 - 11, 2027
Apr 19 - 29, 2027
April 25 - May 9, 2027
May 2 - 11, 2027
National Conference on Wilderness Medicine: Santa Fe, NM
June 2 - 6, 2027
June 11 - 19, 2027
Skills Course Rafting & Mt. Shasta
June 13 - 18, 2027
National Conference on Wilderness Medicine: Big Sky Resort, MT
July 24 - 28, 2027
Deluxe African Safari: Zimbabwe
July 29 - Aug 8, 2027
Aug 29 - Sept 8, 2027
Aug. 29 - Sept. 6, 2027
Middle Fork of the Salmon Rafting
Sept 1-6, 2027
Sept 7 - 15, 2027
Deluxe Peru: Sacred Valley & Machu Picchu
Sept 19 - 26, 2027
Sept 21 - Oct 5, 2027
Oct 31 - Nov 10, 2027
Oct 10 - 23, 2027
Fly Fishing for All Levels - Northern California
Oct 17 - 22, 2027
Jan 29 - Feb 5, 2028
March 12 - 19, 2028
Apr 17 - 27, 2028
April 23 - May 7, 2028
June 8 - 16, 2028
Skills Course Rafting & Mt. Shasta
June 11 - 16, 2028
Deluxe African Safari: Zimbabwe
July 26 - Aug 3, 2028
Aug 27 - Sept 6, 2028
Middle Fork of the Salmon Rafting
Sept 1-6, 2028
Sept 14 - 22, 2028
Sept 28 - Oct 8, 2028
Oct 1 - 15, 2028
Oct 8 - 21, 2028
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Oct 15 - 20, 2028
